BDBM50247207 2-(biphenyl-4-ylsulfonamido)pentanedioic acid::CHEMBL475540
SMILES: OC(=O)CCC(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O
InChI Key: InChIKey=IQGHPUPMOUUHPP-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collagenase 3 (Homo sapiens (Human)) | BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assay | Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP9 by fluorogenic substrate assay | Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Florida Atlantic University Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP13 expressed in Escherichia coli | Bioorg Med Chem 17: 990-1005 (2009) Article DOI: 10.1016/j.bmc.2008.03.004 BindingDB Entry DOI: 10.7270/Q2GB24ZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay | Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP8 by fluorogenic substrate assay | Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D | |||||||||||
More data for this Ligand-Target Pair |