BDBM50247219 (2S,4S)-Methyl 4-((E)-3-(3,4-dimethoxyphenyl)acrylamido)-1-acetylpyrrolidine-2-carboxylate::CHEMBL515766

SMILES: COC(=O)[C@@H]1C[C@@H](CN1C(C)=O)NC(=O)\C=C\c1ccc(OC)c(OC)c1

InChI Key: InChIKey=KGKJMMZCNMIUBO-ODYMAQSMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50247219 ((2S,4S)-Methyl 4-((E)-3-(3,4-dimethoxyphenyl)acryl...) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(C)=O)NC(=O)\C=C\c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C19H24N2O6/c1-12(22)21-11-14(10-15(21)19(24)27-4)20-18(23)8-6-13-5-7-16(25-2)17(9-13)26-3/h5-9,14-15H,10-11H2,1-4H3,(H,20,23)/b8-6+/t14-,15-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase N (unknown origin) by microtiter plate fluorimetric assay				Eur J Med Chem 43: 2130-9 (2008) Article DOI: 10.1016/j.ejmech.2007.12.020 BindingDB Entry DOI: 10.7270/Q22J6BNP
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50247219 ((2S,4S)-Methyl 4-((E)-3-(3,4-dimethoxyphenyl)acryl...) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(C)=O)NC(=O)\C=C\c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C19H24N2O6/c1-12(22)21-11-14(10-15(21)19(24)27-4)20-18(23)8-6-13-5-7-16(25-2)17(9-13)26-3/h5-9,14-15H,10-11H2,1-4H3,(H,20,23)/b8-6+/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 (unknown origin) by microtiter plate fluorimetric assay				Eur J Med Chem 43: 2130-9 (2008) Article DOI: 10.1016/j.ejmech.2007.12.020 BindingDB Entry DOI: 10.7270/Q22J6BNP
					More data for this Ligand-Target Pair