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SMILES: O=C(NCC(=O)N1CCCCC1)Nc1ccc2ccncc2c1

InChI Key: InChIKey=FBRUADXCCZXQEN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247355   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 3


(Homo sapiens)		BDBM50247355
PNG
(CHEMBL4081660)
Show SMILES O=C(NCC(=O)N1CCCCC1)Nc1ccc2ccncc2c1
Show InChI InChI=1S/C17H20N4O2/c22-16(21-8-2-1-3-9-21)12-19-17(23)20-15-5-4-13-6-7-18-11-14(13)10-15/h4-7,10-11H,1-3,8-9,12H2,(H2,19,20,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+3n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...

J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
BindingDB Entry DOI: 10.7270/Q24J0HK6
More data for this
Ligand-Target Pair