null

SMILES: CN1C(=O)\C(Oc2ccccc12)=C\c1ccc(\C=C\C(=O)NCc2cccnc2)s1

InChI Key: InChIKey=XZSDNYHHWDDDFV-SNTPLNSLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50247728 ((E)-3-(5-((Z)-4-Methyl-3-oxo-3,4-dihydrobenzo[b][1...) Show SMILES CN1C(=O)\C(Oc2ccccc12)=C\c1ccc(\C=C\C(=O)NCc2cccnc2)s1 Show InChI InChI=1S/C23H19N3O3S/c1-26-19-6-2-3-7-20(19)29-21(23(26)28)13-18-9-8-17(30-18)10-11-22(27)25-15-16-5-4-12-24-14-16/h2-14H,15H2,1H3,(H,25,27)/b11-10+,21-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of ABL (unknown origin) expressed in baculovirus system by ELISA				Bioorg Med Chem 17: 699-708 (2009) Article DOI: 10.1016/j.bmc.2008.11.060 BindingDB Entry DOI: 10.7270/Q27M07TN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50247728 ((E)-3-(5-((Z)-4-Methyl-3-oxo-3,4-dihydrobenzo[b][1...) Show SMILES CN1C(=O)\C(Oc2ccccc12)=C\c1ccc(\C=C\C(=O)NCc2cccnc2)s1 Show InChI InChI=1S/C23H19N3O3S/c1-26-19-6-2-3-7-20(19)29-21(23(26)28)13-18-9-8-17(30-18)10-11-22(27)25-15-16-5-4-12-24-14-16/h2-14H,15H2,1H3,(H,25,27)/b11-10+,21-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) expressed in baculovirus system by ELISA				Bioorg Med Chem 17: 699-708 (2009) Article DOI: 10.1016/j.bmc.2008.11.060 BindingDB Entry DOI: 10.7270/Q27M07TN
					More data for this Ligand-Target Pair