BDBM50247755 2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-yl]-3-methyl-4(3H)-quinazolinone::CHEMBL460730

SMILES: COc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1nc2ccccc2c(=O)n1C

InChI Key: InChIKey=RDFLQJHKCILDSM-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50247755 (2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-y...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1nc2ccccc2c(=O)n1C |t:9| Show InChI InChI=1S/C23H20N4O3/c1-26-22(28)17-6-3-4-7-18(17)24-23(26)27-20(21-8-5-13-30-21)14-19(25-27)15-9-11-16(29-2)12-10-15/h3-13,20H,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50247755 (2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-y...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1nc2ccccc2c(=O)n1C |t:9| Show InChI InChI=1S/C23H20N4O3/c1-26-22(28)17-6-3-4-7-18(17)24-23(26)27-20(21-8-5-13-30-21)14-19(25-27)15-9-11-16(29-2)12-10-15/h3-13,20H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50247755 (2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-y...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1nc2ccccc2c(=O)n1C |t:9| Show InChI InChI=1S/C23H20N4O3/c1-26-22(28)17-6-3-4-7-18(17)24-23(26)27-20(21-8-5-13-30-21)14-19(25-27)15-9-11-16(29-2)12-10-15/h3-13,20H,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50247755 (2-[(3-(4-Methoxyphenyl)-5'-furyl-2'-pyrazoline-1-y...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1nc2ccccc2c(=O)n1C |t:9| Show InChI InChI=1S/C23H20N4O3/c1-26-22(28)17-6-3-4-7-18(17)24-23(26)27-20(21-8-5-13-30-21)14-19(25-27)15-9-11-16(29-2)12-10-15/h3-13,20H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
					More data for this Ligand-Target Pair