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SMILES: COc1ccc(cc1)-c1cnsc1-c1ccc(Cl)cc1

InChI Key: InChIKey=XGOLGQNTCHMSDA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 1


(Bos taurus)		BDBM50247850
PNG
(5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole ...)
Show SMILES COc1ccc(cc1)-c1cnsc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H12ClNOS/c1-19-14-8-4-11(5-9-14)15-10-18-20-16(15)12-2-6-13(17)7-3-12/h2-10H,1H3
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Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Johannes Gutenberg-University

Curated by ChEMBL


Assay Description
Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC

Bioorg Med Chem 17: 558-68 (2009)


Article DOI: 10.1016/j.bmc.2008.11.074
BindingDB Entry DOI: 10.7270/Q2X92B4S
More data for this
Ligand-Target Pair