BDBM50248063 2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamide::CHEMBL464416

SMILES: CCCS(=O)(=O)N1CCC(CCOC)(CNC(=O)c2ccc(Cl)cc2Cl)CC1

InChI Key: InChIKey=VVYSPESZCSGACZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50248063 (2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...) Show SMILES CCCS(=O)(=O)N1CCC(CCOC)(CNC(=O)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C19H28Cl2N2O4S/c1-3-12-28(25,26)23-9-6-19(7-10-23,8-11-27-2)14-22-18(24)16-5-4-15(20)13-17(16)21/h4-5,13H,3,6-12,14H2,1-2H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of Glyt1				Bioorg Med Chem Lett 19: 1492-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.015 BindingDB Entry DOI: 10.7270/Q2B27V5N
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent taurine transporter (Homo sapiens (Human))	BDBM50248063 (2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...) Show SMILES CCCS(=O)(=O)N1CCC(CCOC)(CNC(=O)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C19H28Cl2N2O4S/c1-3-12-28(25,26)23-9-6-19(7-10-23,8-11-27-2)14-22-18(24)16-5-4-15(20)13-17(16)21/h4-5,13H,3,6-12,14H2,1-2H3,(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of taurine transporter				Bioorg Med Chem Lett 19: 1492-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.015 BindingDB Entry DOI: 10.7270/Q2B27V5N
					More data for this Ligand-Target Pair
Glycine transporter 2 (Homo sapiens (Human))	BDBM50248063 (2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...) Show SMILES CCCS(=O)(=O)N1CCC(CCOC)(CNC(=O)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C19H28Cl2N2O4S/c1-3-12-28(25,26)23-9-6-19(7-10-23,8-11-27-2)14-22-18(24)16-5-4-15(20)13-17(16)21/h4-5,13H,3,6-12,14H2,1-2H3,(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of Glyt2				Bioorg Med Chem Lett 19: 1492-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.015 BindingDB Entry DOI: 10.7270/Q2B27V5N
					More data for this Ligand-Target Pair