BDBM50248094 CHEMBL460922::N-((1-methyl-1'-(propylsulfonyl)-2,4'-bipiperidin-4'-yl)methyl)-2-(trifluoromethoxy)benzamide

SMILES: CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)C1CCCCN1C

InChI Key: InChIKey=IEXOGVRKQGANHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50248094 (CHEMBL460922 | N-((1-methyl-1'-(propylsulfonyl)-2,...) Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)C1CCCCN1C Show InChI InChI=1S/C23H34F3N3O4S/c1-3-16-34(31,32)29-14-11-22(12-15-29,20-10-6-7-13-28(20)2)17-27-21(30)18-8-4-5-9-19(18)33-23(24,25)26/h4-5,8-9,20H,3,6-7,10-17H2,1-2H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of human glycine transporter 1				Bioorg Med Chem Lett 19: 1488-91 (2009) Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3
					More data for this Ligand-Target Pair