BDBM50248275 CHEMBL474751::N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)acrylamide

SMILES: Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ncccc4c3)cccc12

InChI Key: InChIKey=IQNCDVXBDIXEMM-KPKJPENVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50248275 (CHEMBL474751 | N-(3,4-difluorophenylsulfonyl)-3-(1...) Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H19F2N3O4S/c1-32-16-18(7-12-26(33)31-37(34,35)20-9-10-21(28)22(29)15-20)27-24(32)5-2-6-25(27)36-19-8-11-23-17(14-19)4-3-13-30-23/h2-16H,1H3,(H,31,33)/b12-7+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum				Bioorg Med Chem Lett 19: 1528-31 (2009) Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50248275 (CHEMBL474751 | N-(3,4-difluorophenylsulfonyl)-3-(1...) Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H19F2N3O4S/c1-32-16-18(7-12-26(33)31-37(34,35)20-9-10-21(28)22(29)15-20)27-24(32)5-2-6-25(27)36-19-8-11-23-17(14-19)4-3-13-30-23/h2-16H,1H3,(H,31,33)/b12-7+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer				Bioorg Med Chem Lett 19: 1528-31 (2009) Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0
					More data for this Ligand-Target Pair