BDBM50248387 2-amino-5-(ethylthio)-N-(4-methylthiazol-2-yl)benzamide::CHEMBL451084

SMILES: CCSc1ccc(N)c(c1)C(=O)Nc1nc(C)cs1

InChI Key: InChIKey=RJTBVUQMPODIAS-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase-4 (Homo sapiens (Human))	BDBM50248387 (2-amino-5-(ethylthio)-N-(4-methylthiazol-2-yl)benz...) Show SMILES CCSc1ccc(N)c(c1)C(=O)Nc1nc(C)cs1 Show InChI InChI=1S/C13H15N3OS2/c1-3-18-9-4-5-11(14)10(6-9)12(17)16-13-15-8(2)7-19-13/h4-7H,3,14H2,1-2H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucose				Bioorg Med Chem Lett 19: 1357-60 (2009) Article DOI: 10.1016/j.bmcl.2009.01.053 BindingDB Entry DOI: 10.7270/Q2PC3285
					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50248387 (2-amino-5-(ethylthio)-N-(4-methylthiazol-2-yl)benz...) Show SMILES CCSc1ccc(N)c(c1)C(=O)Nc1nc(C)cs1 Show InChI InChI=1S/C13H15N3OS2/c1-3-18-9-4-5-11(14)10(6-9)12(17)16-13-15-8(2)7-19-13/h4-7H,3,14H2,1-2H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucose				Bioorg Med Chem Lett 19: 1357-60 (2009) Article DOI: 10.1016/j.bmcl.2009.01.053 BindingDB Entry DOI: 10.7270/Q2PC3285
					More data for this Ligand-Target Pair