Found 3 hits for monomerid = 50248664 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50248664
(CHEMBL465426 | N-((1-(propylsulfonyl)-4-(pyridin-2...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O3S/c1-2-15-32(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of glycine transporter 2 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50248664
(CHEMBL465426 | N-((1-(propylsulfonyl)-4-(pyridin-2...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O3S/c1-2-15-32(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of taurine transporter |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50248664
(CHEMBL465426 | N-((1-(propylsulfonyl)-4-(pyridin-2...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2C(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O3S/c1-2-15-32(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description Inhibition of human glycine transporter 1 |
Bioorg Med Chem Lett 19: 1488-91 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3 |
More data for this Ligand-Target Pair | |