BDBM50248665 CHEMBL517034::N-((1-(propylsulfonyl)-4-(pyridin-2-yl)piperidin-4-yl)methyl)-2-(trifluoromethoxy)benzamide

SMILES: CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)c1ccccn1

InChI Key: InChIKey=SGUCGVARECBSMD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 2 (Homo sapiens (Human))	BDBM50248665 (CHEMBL517034 | N-((1-(propylsulfonyl)-4-(pyridin-2...) Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O4S/c1-2-15-33(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)32-22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of glycine transporter 2				Bioorg Med Chem Lett 19: 1488-91 (2009) Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent taurine transporter (Homo sapiens (Human))	BDBM50248665 (CHEMBL517034 | N-((1-(propylsulfonyl)-4-(pyridin-2...) Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O4S/c1-2-15-33(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)32-22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of taurine transporter				Bioorg Med Chem Lett 19: 1488-91 (2009) Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM50248665 (CHEMBL517034 | N-((1-(propylsulfonyl)-4-(pyridin-2...) Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(CC1)c1ccccn1 Show InChI InChI=1S/C22H26F3N3O4S/c1-2-15-33(30,31)28-13-10-21(11-14-28,19-9-5-6-12-26-19)16-27-20(29)17-7-3-4-8-18(17)32-22(23,24)25/h3-9,12H,2,10-11,13-16H2,1H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of human glycine transporter 1				Bioorg Med Chem Lett 19: 1488-91 (2009) Article DOI: 10.1016/j.bmcl.2008.12.115 BindingDB Entry DOI: 10.7270/Q2V124P3
					More data for this Ligand-Target Pair