BDBM50248738 2-(2-Chlorophenyl)-N,N',4-trimethyl-10Hphenothiazine-1,3-dicarboxamide::CHEMBL518832

SMILES: CNC(=O)c1c(C)c2Sc3ccccc3Nc2c(C(=O)NC)c1-c1ccccc1Cl

InChI Key: InChIKey=LWLKPLCGQDUABA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-glutamyltranspeptidase 1 (Homo sapiens (Human))	BDBM50248738 (2-(2-Chlorophenyl)-N,N',4-trimethyl-10Hphenothiazi...) Show SMILES CNC(=O)c1c(C)c2Sc3ccccc3Nc2c(C(=O)NC)c1-c1ccccc1Cl |(29.29,-26.84,;27.96,-27.61,;27.97,-29.15,;29.31,-29.91,;26.64,-29.93,;25.3,-29.17,;25.28,-27.63,;23.96,-29.95,;22.61,-29.17,;21.28,-29.96,;19.94,-29.2,;18.61,-29.97,;18.61,-31.51,;19.95,-32.28,;21.28,-31.51,;22.62,-32.28,;23.97,-31.5,;25.31,-32.27,;25.32,-33.81,;26.66,-34.57,;23.99,-34.58,;24,-36.12,;26.66,-31.49,;27.99,-32.25,;28,-33.78,;29.33,-34.55,;30.66,-33.77,;30.65,-32.22,;29.31,-31.47,;30.63,-30.69,)| Show InChI InChI=1S/C23H20ClN3O2S/c1-12-17(22(28)25-2)18(13-8-4-5-9-14(13)24)19(23(29)26-3)20-21(12)30-16-11-7-6-10-15(16)27-20/h4-11,27H,1-3H3,(H,25,28)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of gamma-glutamyltranspeptidase (unknown origin) by colorimetric assay				Eur J Med Chem 44: 197-202 (2008) Article DOI: 10.1016/j.ejmech.2008.02.028 BindingDB Entry DOI: 10.7270/Q20K28B1
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