BDBM50248770 2-(2-Methoxyphenyl)-N,N',4-trimethyl-10Hphenothiazine-1,3-dicarboxamide::CHEMBL473585

SMILES: CNC(=O)c1c(C)c2Sc3ccccc3Nc2c(C(=O)NC)c1-c1ccccc1OC

InChI Key: InChIKey=SGLCGLLOKYJDBL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-glutamyltranspeptidase 1 (Homo sapiens (Human))	BDBM50248770 (2-(2-Methoxyphenyl)-N,N',4-trimethyl-10Hphenothiaz...) Show SMILES CNC(=O)c1c(C)c2Sc3ccccc3Nc2c(C(=O)NC)c1-c1ccccc1OC |(14.81,-40.77,;13.29,-41.54,;13.28,-43.08,;14.61,-43.85,;11.94,-43.85,;10.6,-43.08,;10.6,-41.54,;9.27,-43.85,;7.94,-43.08,;6.6,-43.85,;5.27,-43.08,;3.93,-43.85,;3.93,-45.39,;5.27,-46.16,;6.6,-45.39,;7.94,-46.16,;9.27,-45.39,;10.6,-46.16,;10.6,-47.7,;11.93,-48.47,;9.26,-48.47,;9.26,-50.02,;11.93,-45.39,;13.4,-45.86,;14.21,-44.5,;15.75,-44.54,;16.49,-45.89,;15.68,-47.21,;14.14,-47.16,;13.46,-48.47,;14.45,-49.92,)| Show InChI InChI=1S/C24H23N3O3S/c1-13-18(23(28)25-2)19(14-9-5-7-11-16(14)30-4)20(24(29)26-3)21-22(13)31-17-12-8-6-10-15(17)27-21/h5-12,27H,1-4H3,(H,25,28)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of gamma-glutamyltranspeptidase (unknown origin) by colorimetric assay				Eur J Med Chem 44: 197-202 (2008) Article DOI: 10.1016/j.ejmech.2008.02.028 BindingDB Entry DOI: 10.7270/Q20K28B1
					More data for this Ligand-Target Pair