BDBM50248837 CHEMBL4097969

SMILES: Fc1ccc(Oc2ccc3cc4C(=O)NC(=S)n4c(=O)c3c2)cc1

InChI Key: InChIKey=BFUHGXWBGZDJNH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248837 (CHEMBL4097969) Show SMILES Fc1ccc(Oc2ccc3cc4C(=O)NC(=S)n4c(=O)c3c2)cc1 Show InChI InChI=1S/C17H9FN2O3S/c18-10-2-5-11(6-3-10)23-12-4-1-9-7-14-15(21)19-17(24)20(14)16(22)13(9)8-12/h1-8H,(H,19,21,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair