BDBM50248840 CHEMBL4096175

SMILES: Clc1cc2NC3C(C=C4N(C(=S)NC4=O)C3=O)c2c(Cl)c1

InChI Key: InChIKey=XUIHLAZYWIQDIJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248840 (CHEMBL4096175) Show SMILES Clc1cc2NC3C(C=C4N(C(=S)NC4=O)C3=O)c2c(Cl)c1 |c:7| Show InChI InChI=1S/C13H7Cl2N3O2S/c14-4-1-6(15)9-5-3-8-11(19)17-13(21)18(8)12(20)10(5)16-7(9)2-4/h1-3,5,10,16H,(H,17,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair