BDBM50248865 CHEMBL4069055

SMILES: Cn1c(\C=C2/SC(=S)NC2=O)cc2sccc12

InChI Key: InChIKey=KODXSOUJVHJCNY-UITAMQMPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248865 (CHEMBL4069055) Show SMILES Cn1c(\C=C2/SC(=S)NC2=O)cc2sccc12 Show InChI InChI=1S/C11H8N2OS3/c1-13-6(4-8-7(13)2-3-16-8)5-9-10(14)12-11(15)17-9/h2-5H,1H3,(H,12,14,15)/b9-5-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair