BDBM50248903 CHEMBL4060012

SMILES: CN1CCN(CC1)c1cc(ccn1)-c1nc(\C=C2/SC(=S)NC2=O)cs1

InChI Key: InChIKey=UFITZYYLKHOVAI-LCYFTJDESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248903 (CHEMBL4060012) Show SMILES CN1CCN(CC1)c1cc(ccn1)-c1nc(\C=C2/SC(=S)NC2=O)cs1 Show InChI InChI=1S/C17H17N5OS3/c1-21-4-6-22(7-5-21)14-8-11(2-3-18-14)16-19-12(10-25-16)9-13-15(23)20-17(24)26-13/h2-3,8-10H,4-7H2,1H3,(H,20,23,24)/b13-9-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair