BDBM50248921 CHEMBL4096030

SMILES: CS(=O)(=O)c1ccc(cc1)-c1nc(\C=C2/SC(=S)NC2=O)cs1

InChI Key: InChIKey=VEBPNWGXHTZMDK-WDZFZDKYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50248921 (CHEMBL4096030) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(\C=C2/SC(=S)NC2=O)cs1 Show InChI InChI=1S/C14H10N2O3S4/c1-23(18,19)10-4-2-8(3-5-10)13-15-9(7-21-13)6-11-12(17)16-14(20)22-11/h2-7H,1H3,(H,16,17,20)/b11-6-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay				Bioorg Med Chem 25: 2657-2665 (2017) Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V
					More data for this Ligand-Target Pair