BDBM50249325 CHEMBL472609::N-(5-chloropyridin-2-yl)-3-(4-(N,N-dimethylcarbamimidoyl)benzamido)thiophene-2-carboxamide

SMILES: CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccsc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=NTATYANFBIDWNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50249325 (CHEMBL472609 | N-(5-chloropyridin-2-yl)-3-(4-(N,N-...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccsc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C20H18ClN5O2S/c1-26(2)18(22)12-3-5-13(6-4-12)19(27)24-15-9-10-29-17(15)20(28)25-16-8-7-14(21)11-23-16/h3-11,22H,1-2H3,(H,24,27)(H,23,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair