BDBM50249459 (4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(5-phenylpyridin-2-yl)methanone::CHEMBL472415

SMILES: O=C(N1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(cn1)-c1ccccc1

InChI Key: InChIKey=XLAQCDVBVVLGIG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50249459 ((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(5-phe...) Show SMILES O=C(N1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C24H22N4O/c29-24(22-11-10-19(16-25-22)17-6-2-1-3-7-17)28-14-12-18(13-15-28)23-26-20-8-4-5-9-21(20)27-23/h1-11,16,18H,12-15H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceutical Curated by ChEMBL					Assay Description Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...				Bioorg Med Chem Lett 19: 2206-10 (2009) Article DOI: 10.1016/j.bmcl.2009.02.126 BindingDB Entry DOI: 10.7270/Q20Z735D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50249459 ((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(5-phe...) Show SMILES O=C(N1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C24H22N4O/c29-24(22-11-10-19(16-25-22)17-6-2-1-3-7-17)28-14-12-18(13-15-28)23-26-20-8-4-5-9-21(20)27-23/h1-11,16,18H,12-15H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceutical Curated by ChEMBL					Assay Description Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...				Bioorg Med Chem Lett 19: 2206-10 (2009) Article DOI: 10.1016/j.bmcl.2009.02.126 BindingDB Entry DOI: 10.7270/Q20Z735D
					More data for this Ligand-Target Pair