null

SMILES: COc1cc(SC)ccc1C(=O)Nc1cccc(C)n1

InChI Key: InChIKey=PHZLUOIEBZHRQC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249572 (CHEMBL1463447 | US10729695, Compound CB-1) Show SMILES COc1cc(SC)ccc1C(=O)Nc1cccc(C)n1 Show InChI InChI=1S/C15H16N2O2S/c1-10-5-4-6-14(16-10)17-15(18)12-8-7-11(20-3)9-13(12)19-2/h4-9H,1-3H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	US Patent	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020)
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249572 (CHEMBL1463447 | US10729695, Compound CB-1) Show SMILES COc1cc(SC)ccc1C(=O)Nc1cccc(C)n1 Show InChI InChI=1S/C15H16N2O2S/c1-10-5-4-6-14(16-10)17-15(18)12-8-7-11(20-3)9-13(12)19-2/h4-9H,1-3H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair