BDBM50249759 10-(2-(diethylamino)ethyl)acridin-9(10H)-one::CHEMBL444412::KF-A2
SMILES: CCN(CC)CCn1c2ccccc2c(=O)c2ccccc12
InChI Key: InChIKey=RINBNPPEMJIWTC-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50249759 (10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Veterans Affairs Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells | Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50249759 (10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Veterans Affairs Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells | Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50249759 (10-(2-(diethylamino)ethyl)acridin-9(10H)-one | CHE...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Veterans Affairs Medical Center Curated by ChEMBL | Assay Description Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cells | Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ | |||||||||||
More data for this Ligand-Target Pair |