BDBM50249780 10-(3-(diethylamino)propyl)acridin-9(10H)-one::CHEMBL491753::KF-A3

SMILES: CCN(CC)CCCn1c2ccccc2c(=O)c2ccccc12

InChI Key: InChIKey=KHFAFXFRTUHQNO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50249780 (10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...) Show SMILES CCN(CC)CCCn1c2ccccc2c(=O)c2ccccc12 Show InChI InChI=1S/C20H24N2O/c1-3-21(4-2)14-9-15-22-18-12-7-5-10-16(18)20(23)17-11-6-8-13-19(17)22/h5-8,10-13H,3-4,9,14-15H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells				Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50249780 (10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...) Show SMILES CCN(CC)CCCn1c2ccccc2c(=O)c2ccccc12 Show InChI InChI=1S/C20H24N2O/c1-3-21(4-2)14-9-15-22-18-12-7-5-10-16(18)20(23)17-11-6-8-13-19(17)22/h5-8,10-13H,3-4,9,14-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells				Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50249780 (10-(3-(diethylamino)propyl)acridin-9(10H)-one | CH...) Show SMILES CCN(CC)CCCn1c2ccccc2c(=O)c2ccccc12 Show InChI InChI=1S/C20H24N2O/c1-3-21(4-2)14-9-15-22-18-12-7-5-10-16(18)20(23)17-11-6-8-13-19(17)22/h5-8,10-13H,3-4,9,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cells				Antimicrob Agents Chemother 51: 4133-40 (2007) Article DOI: 10.1128/AAC.00669-07 BindingDB Entry DOI: 10.7270/Q2FT8MZZ
					More data for this Ligand-Target Pair