BDBM50249809 CHEMBL4080511

SMILES: CCc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O

InChI Key: InChIKey=SFLJDWKPAAAKBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50249809 (CHEMBL4080511) Show SMILES CCc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O Show InChI InChI=1S/C19H17N3O3S/c1-3-14-10-15-11-16(6-9-18(15)22(2)19(14)23)21-26(24,25)17-7-4-13(12-20)5-8-17/h4-11,21H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of human BRPF1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assay				J Med Chem 60: 668-680 (2017) Article DOI: 10.1021/acs.jmedchem.6b01583 BindingDB Entry DOI: 10.7270/Q29K4DQ5
					More data for this Ligand-Target Pair