null

SMILES: OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=ABEDQOQTISCLFO-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50250099 ((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...) Show SMILES OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H28BN3O4/c30-24(21-12-8-16-27-18-21)29-23(14-5-2-6-15-26(32)33)25(31)28-22-13-7-11-20(17-22)19-9-3-1-4-10-19/h1,3-4,7-13,16-18,23,32-33H,2,5-6,14-15H2,(H,28,31)(H,29,30)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 by fluorometry				J Med Chem 52: 2909-22 (2009) Article DOI: 10.1021/jm900125m BindingDB Entry DOI: 10.7270/Q2HH6JZW
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50250099 ((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...) Show SMILES OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H28BN3O4/c30-24(21-12-8-16-27-18-21)29-23(14-5-2-6-15-26(32)33)25(31)28-22-13-7-11-20(17-22)19-9-3-1-4-10-19/h1,3-4,7-13,16-18,23,32-33H,2,5-6,14-15H2,(H,28,31)(H,29,30)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 by fluorometry				J Med Chem 52: 2909-22 (2009) Article DOI: 10.1021/jm900125m BindingDB Entry DOI: 10.7270/Q2HH6JZW
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50250099 ((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...) Show SMILES OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H28BN3O4/c30-24(21-12-8-16-27-18-21)29-23(14-5-2-6-15-26(32)33)25(31)28-22-13-7-11-20(17-22)19-9-3-1-4-10-19/h1,3-4,7-13,16-18,23,32-33H,2,5-6,14-15H2,(H,28,31)(H,29,30)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 by fluorometry				J Med Chem 52: 2909-22 (2009) Article DOI: 10.1021/jm900125m BindingDB Entry DOI: 10.7270/Q2HH6JZW
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50250099 ((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...) Show SMILES OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H28BN3O4/c30-24(21-12-8-16-27-18-21)29-23(14-5-2-6-15-26(32)33)25(31)28-22-13-7-11-20(17-22)19-9-3-1-4-10-19/h1,3-4,7-13,16-18,23,32-33H,2,5-6,14-15H2,(H,28,31)(H,29,30)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 by fluorometry				J Med Chem 52: 2909-22 (2009) Article DOI: 10.1021/jm900125m BindingDB Entry DOI: 10.7270/Q2HH6JZW
					More data for this Ligand-Target Pair