BDBM50250369 CHEMBL4099285

SMILES: CC[C@@H]1C[C@@H](C[C@H](Cc2ccccc2)N1C(=O)OC(C)(C)C)N(Cc1cc(OC)cc(c1)C(F)(F)F)c1ncc(Br)cn1

InChI Key: InChIKey=QVYBBHNZDUNNTK-PVHODMMVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50250369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50250369 (CHEMBL4099285) Show SMILES CC[C@@H]1C[C@@H](C[C@H](Cc2ccccc2)N1C(=O)OC(C)(C)C)N(Cc1cc(OC)cc(c1)C(F)(F)F)c1ncc(Br)cn1 |r| Show InChI InChI=1S/C32H38BrF3N4O3/c1-6-25-16-26(17-27(13-21-10-8-7-9-11-21)40(25)30(41)43-31(2,3)4)39(29-37-18-24(33)19-38-29)20-22-12-23(32(34,35)36)15-28(14-22)42-5/h7-12,14-15,18-19,25-27H,6,13,16-17,20H2,1-5H3/t25-,26+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research, Inc. Curated by ChEMBL					Assay Description Inhibition of CETP in human plasma measured every 30 mins for 120 mins by fluorescence method				J Med Chem 60: 8466-8481 (2017) Article DOI: 10.1021/acs.jmedchem.7b00900 BindingDB Entry DOI: 10.7270/Q27083WQ
					More data for this Ligand-Target Pair