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BDBM50250592 CHEMBL4095079

SMILES: C(Nc1cccnc1)c1cn(Cc2ccccc2)c2ccccc12

InChI Key: InChIKey=FXRHZHGEENHPFI-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50250592   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50250592
PNG
(CHEMBL4095079)
Show SMILES C(Nc1cccnc1)c1cn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C21H19N3/c1-2-7-17(8-3-1)15-24-16-18(20-10-4-5-11-21(20)24)13-23-19-9-6-12-22-14-19/h1-12,14,16,23H,13,15H2
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Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Universidad Complutense de Madrid

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human 5-HT2C receptor expressed in human HeLa-K1 cells assessed as potentiation of 5-HT-induced inositol monophosph...

J Med Chem 60: 9575-9584 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00994
BindingDB Entry DOI: 10.7270/Q2SQ92SJ
More data for this
Ligand-Target Pair