BDBM50250887 CHEMBL4077375

SMILES: CC(=O)N1CCc2c(C1)cc(-c1cccc(Cl)c1)c(=O)n2CC1CC1

InChI Key: InChIKey=QPIADADOJOQULY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50250887 (CHEMBL4077375) Show SMILES CC(=O)N1CCc2c(C1)cc(-c1cccc(Cl)c1)c(=O)n2CC1CC1 Show InChI InChI=1S/C20H21ClN2O2/c1-13(24)22-8-7-19-16(12-22)10-18(15-3-2-4-17(21)9-15)20(25)23(19)11-14-5-6-14/h2-4,9-10,14H,5-8,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of His tagged recombinant BRD4 bromodomain 1 (unknown origin) by TR-FRET assay				J Med Chem 60: 10151-10171 (2017) Article DOI: 10.1021/acs.jmedchem.7b01372 BindingDB Entry DOI: 10.7270/Q27S7R65
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50250887 (CHEMBL4077375) Show SMILES CC(=O)N1CCc2c(C1)cc(-c1cccc(Cl)c1)c(=O)n2CC1CC1 Show InChI InChI=1S/C20H21ClN2O2/c1-13(24)22-8-7-19-16(12-22)10-18(15-3-2-4-17(21)9-15)20(25)23(19)11-14-5-6-14/h2-4,9-10,14H,5-8,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of His tagged recombinant CBP (unknown origin) by TR-FRET assay				J Med Chem 60: 10151-10171 (2017) Article DOI: 10.1021/acs.jmedchem.7b01372 BindingDB Entry DOI: 10.7270/Q27S7R65
					More data for this Ligand-Target Pair