BDBM50251012 CHEMBL465879::broussonin A
SMILES: COc1ccc(CCCc2ccc(O)cc2)c(O)c1
InChI Key: InChIKey=MSNVBURPCQDLEP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cytochrome P450 19A1 (Homo sapiens (Human)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of aromatase from human placental microsomes | J Nat Prod 64: 1286-93 (2001) BindingDB Entry DOI: 10.7270/Q2RB74C4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Displacement of [3H]17-beta-estradiol from human recombinant full length ERalpha | Bioorg Med Chem Lett 20: 3764-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.064 BindingDB Entry DOI: 10.7270/Q2DR2VP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic lipase (Sus scrofa (Pig)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate preincubated for 15 mins prior substrate addition measured after 15 ... | Bioorg Med Chem Lett 22: 2760-3 (2012) Article DOI: 10.1016/j.bmcl.2012.02.088 BindingDB Entry DOI: 10.7270/Q2H41SFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Transactivation of human recombinant ERalpha expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter ge... | Bioorg Med Chem Lett 20: 3764-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.064 BindingDB Entry DOI: 10.7270/Q2DR2VP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Transactivation of human recombinant ERbeta expressed in african green monkey CV1 cells co-expressing ERE-Luc after 24 hrs by luciferase reporter gen... | Bioorg Med Chem Lett 20: 3764-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.064 BindingDB Entry DOI: 10.7270/Q2DR2VP0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM50251012 (CHEMBL465879 | broussonin A) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sookmyung Women's University Curated by ChEMBL | Assay Description Displacement of [3H]17-beta-estradiol from human recombinant full length ERbeta | Bioorg Med Chem Lett 20: 3764-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.064 BindingDB Entry DOI: 10.7270/Q2DR2VP0 | |||||||||||
More data for this Ligand-Target Pair |