BindingDB PrimarySearch

BDBM50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054

SMILES: CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1

InChI Key: InChIKey=NJWHLJABYCIZPL-LJQANCHMSA-N

Data: 5 KI 2 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50251026
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cells				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2short receptor expressed in CHO-K1 cells by liquid scintillation counting				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membrane				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in Ltk deficient fibroblast cells by liquid scintillation counting				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from human cloned dopamine D2 receptor expressed in CHO cell membrane				Bioorg Med Chem 16: 4563-8 (2008) Article DOI: 10.1016/j.bmc.2008.02.038 BindingDB Entry DOI: 10.7270/Q24J0DW0
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cells				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membrane				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair