BDBM50251306 CHEMBL4085528

SMILES: Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)-c1ccc(F)c(Cl)c1

InChI Key: InChIKey=GHRMVCBSQIPOAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50251306 (CHEMBL4085528) Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C25H17ClFN5O3/c1-14-12-22(33)32(16-4-7-20(27)19(26)13-16)31-23(14)25(34)30-15-2-5-17(6-3-15)35-21-9-11-29-24-18(21)8-10-28-24/h2-13H,1H3,(H,28,29)(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com. Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Eur J Med Chem 133: 97-106 (2017) Article DOI: 10.1016/j.ejmech.2017.03.045 BindingDB Entry DOI: 10.7270/Q2K35X3B
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