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BDBM50251317 CHEMBL4061741

SMILES: Cc1ccc(C)c(c1)-n1nc(C(=O)Nc2ccc(Oc3ccnc4n(C)ccc34)cc2)c(C)cc1=O

InChI Key: InChIKey=IOTYSUPLJNTOND-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251317   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50251317
PNG
(CHEMBL4061741)
Show SMILES Cc1ccc(C)c(c1)-n1nc(C(=O)Nc2ccc(Oc3ccnc4n(C)ccc34)cc2)c(C)cc1=O
Show InChI InChI=1S/C28H25N5O3/c1-17-5-6-18(2)23(15-17)33-25(34)16-19(3)26(31-33)28(35)30-20-7-9-21(10-8-20)36-24-11-13-29-27-22(24)12-14-32(27)4/h5-16H,1-4H3,(H,30,35)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 41n/an/an/an/an/an/a



School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com.

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Eur J Med Chem 133: 97-106 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.045
BindingDB Entry DOI: 10.7270/Q2K35X3B
More data for this
Ligand-Target Pair