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SMILES: CCc1cccc(CC)c1-c1cc(OC(C)C)c2C(CCCc2n1)Nc1ccccc1CCO

InChI Key: InChIKey=OTZFBBYPIRPLBY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251460   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor 1


(Homo sapiens (Human))		BDBM50251460
PNG
((+/-)-2-(2-(2-(2,6-diethylphenyl)-4-isopropoxy-5,6...)
Show SMILES CCc1cccc(CC)c1-c1cc(OC(C)C)c2C(CCCc2n1)Nc1ccccc1CCO
Show InChI InChI=1S/C30H38N2O2/c1-5-21-12-9-13-22(6-2)29(21)27-19-28(34-20(3)4)30-25(15-10-16-26(30)32-27)31-24-14-8-7-11-23(24)17-18-33/h7-9,11-14,19-20,25,31,33H,5-6,10,15-18H2,1-4H3
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Similars
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 18: 3852-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.059
BindingDB Entry DOI: 10.7270/Q2765F4X
More data for this
Ligand-Target Pair