BDBM50251600 (+/-)-[2-(2,6-Diethyl-phenyl)-4-methoxy-5,6,7,8-tetrahydro-quinolin-5-yl]-methyl-(4-methyl-biphenyl-3-yl)-amine::CHEMBL480697

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1cc(ccc1C)-c1ccccc1

InChI Key: InChIKey=TXGBDGSJDNPZIL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50251600 ((+/-)-[2-(2,6-Diethyl-phenyl)-4-methoxy-5,6,7,8-te...) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1cc(ccc1C)-c1ccccc1 Show InChI InChI=1S/C34H38N2O/c1-6-24-15-11-16-25(7-2)33(24)29-22-32(37-5)34-28(35-29)17-12-18-30(34)36(4)31-21-27(20-19-23(31)3)26-13-9-8-10-14-26/h8-11,13-16,19-22,30H,6-7,12,17-18H2,1-5H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
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