BDBM50251634 (+/-)-N-(2-chloro-5-methoxyphenyl)-2-(2,6-diethylphenyl)-4-methoxy-N-methyl-5,6,7,8-tetrahydroquinolin-5-amine::CHEMBL480128

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1cc(OC)ccc1Cl

InChI Key: InChIKey=OCFYSUBUVGRBOV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50251634 ((+/-)-N-(2-chloro-5-methoxyphenyl)-2-(2,6-diethylp...) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N(C)c1cc(OC)ccc1Cl Show InChI InChI=1S/C28H33ClN2O2/c1-6-18-10-8-11-19(7-2)27(18)23-17-26(33-5)28-22(30-23)12-9-13-24(28)31(3)25-16-20(32-4)14-15-21(25)29/h8,10-11,14-17,24H,6-7,9,12-13H2,1-5H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair