BDBM50251750 (3-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-ylamino)-4-methylphenyl)methanol::CHEMBL519595

SMILES: CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(CO)ccc1C

InChI Key: InChIKey=ZPQBDCPWRMYVJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50251750 ((3-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrah...) Show SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(CO)ccc1C Show InChI InChI=1S/C28H34N2O2/c1-5-20-9-7-10-21(6-2)27(20)25-16-26(32-4)28-22(11-8-12-23(28)30-25)29-24-15-19(17-31)14-13-18(24)3/h7,9-10,13-16,22,29,31H,5-6,8,11-12,17H2,1-4H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair