null

SMILES: OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3Cl)cc2)cc1

InChI Key: InChIKey=XAVYYOSTYICIOH-NUNAXRQHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251776 (CHEMBL520746 | endo-4-((3-(4-(2-chlorophenoxy)phen...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3Cl)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H27ClN2O3/c28-25-3-1-2-4-26(25)33-24-13-9-20(10-14-24)29-21-15-22-11-12-23(16-21)30(22)17-18-5-7-19(8-6-18)27(31)32/h1-10,13-14,21-23,29H,11-12,15-17H2,(H,31,32)/t21-,22+,23-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in human whole blood				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251776 (CHEMBL520746 | endo-4-((3-(4-(2-chlorophenoxy)phen...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3Cl)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H27ClN2O3/c28-25-3-1-2-4-26(25)33-24-13-9-20(10-14-24)29-21-15-22-11-12-23(16-21)30(22)17-18-5-7-19(8-6-18)27(31)32/h1-10,13-14,21-23,29H,11-12,15-17H2,(H,31,32)/t21-,22+,23-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase (unknown origin)				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair