BDBM50251901 CHEMBL479404::ethyl 2-(2-(2-(phenylsulfonyl)acetamido)thiazol-4-yl)acetate

SMILES: CCOC(=O)Cc1csc(NC(=O)CS(=O)(=O)c2ccccc2)n1

InChI Key: InChIKey=HSROTFIOLUBXTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50251901 (CHEMBL479404 | ethyl 2-(2-(2-(phenylsulfonyl)aceta...) Show SMILES CCOC(=O)Cc1csc(NC(=O)CS(=O)(=O)c2ccccc2)n1 Show InChI InChI=1S/C15H16N2O5S2/c1-2-22-14(19)8-11-9-23-15(16-11)17-13(18)10-24(20,21)12-6-4-3-5-7-12/h3-7,9H,2,8,10H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assay				Bioorg Med Chem Lett 18: 3925-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.031 BindingDB Entry DOI: 10.7270/Q2XW4JM5
					More data for this Ligand-Target Pair