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SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCCc2cccs2)c1

InChI Key: InChIKey=PNFHYGOAHZSEER-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251912   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50251912
PNG
(CHEMBL519617 | {4-[4-(4-Fluoro-phenyl)-2-methylsul...)
Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCCc2cccs2)c1
Show InChI InChI=1S/C21H19FN4S2/c1-27-21-25-19(14-4-6-16(22)7-5-14)20(26-21)15-8-10-23-18(13-15)24-11-9-17-3-2-12-28-17/h2-8,10,12-13H,9,11H2,1H3,(H,23,24)(H,25,26)
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Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair