BDBM50251928 2-{4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-ylamino}-ethanol::CHEMBL480951

SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCCO)c1

InChI Key: InChIKey=OSQFNXDYWMUZLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251928 (2-{4-[4-(4-Fluoro-phenyl)-2-methylsulfanyl-1H-imid...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NCCO)c1 Show InChI InChI=1S/C17H17FN4OS/c1-24-17-21-15(11-2-4-13(18)5-3-11)16(22-17)12-6-7-19-14(10-12)20-8-9-23/h2-7,10,23H,8-9H2,1H3,(H,19,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair