BDBM50251967 CHEMBL482113::{4-[2-Methylsulfanyl-4-(3-trifluoromethyl-phenyl)-1H-imidazol-5-yl]-pyridin-2-yl}-(2-phenylpropyl)-amine

SMILES: CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(NCC(C)c2ccccc2)c1

InChI Key: InChIKey=BYIAYENVBGBGEU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251967 (CHEMBL482113 | {4-[2-Methylsulfanyl-4-(3-trifluoro...) Show SMILES CSc1nc(c([nH]1)-c1cccc(c1)C(F)(F)F)-c1ccnc(NCC(C)c2ccccc2)c1 Show InChI InChI=1S/C25H23F3N4S/c1-16(17-7-4-3-5-8-17)15-30-21-14-19(11-12-29-21)23-22(31-24(32-23)33-2)18-9-6-10-20(13-18)25(26,27)28/h3-14,16H,15H2,1-2H3,(H,29,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair