BDBM50251972 ((R)-1-Cyclohexyl-ethyl)-{4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl-amine::CHEMBL481913

SMILES: CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(N[C@H](C)C2CCCCC2)c1

InChI Key: InChIKey=CWKBMMKCFAOXDL-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251972 (((R)-1-Cyclohexyl-ethyl)-{4-[4-(4-fluoro-phenyl)-2...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(N[C@H](C)C2CCCCC2)c1 |r| Show InChI InChI=1S/C23H27FN4S/c1-15(16-6-4-3-5-7-16)26-20-14-18(12-13-25-20)22-21(27-23(28-22)29-2)17-8-10-19(24)11-9-17/h8-16H,3-7H2,1-2H3,(H,25,26)(H,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 51: 4122-49 (2008) Article DOI: 10.1021/jm701529q BindingDB Entry DOI: 10.7270/Q2W37X67
					More data for this Ligand-Target Pair