BDBM50251997 2-(3-hydroxy-2-(2-phenoxyacetamido)-2,3-dihydrothiazol-4-yl)acetic acid::CHEMBL447601

SMILES: OC(=O)Cc1csc(=NC(=O)COc2ccccc2)n1O

InChI Key: InChIKey=QXVSJDRBRXTZGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50251997 (2-(3-hydroxy-2-(2-phenoxyacetamido)-2,3-dihydrothi...) Show SMILES OC(=O)Cc1csc(=NC(=O)COc2ccccc2)n1O |w:8.8| Show InChI InChI=1S/C13H12N2O5S/c16-11(7-20-10-4-2-1-3-5-10)14-13-15(19)9(8-21-13)6-12(17)18/h1-5,8,19H,6-7H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assay				Bioorg Med Chem Lett 18: 3925-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.031 BindingDB Entry DOI: 10.7270/Q2XW4JM5
					More data for this Ligand-Target Pair