BDBM50252000 2-(3-hydroxy-2-(2-(methylsulfonyl)acetamido)-2,3-dihydrothiazol-4-yl)acetic acid::CHEMBL453519

SMILES: CS(=O)(=O)CC(=O)N=c1scc(CC(O)=O)n1O

InChI Key: InChIKey=LJVAVRBIRBGPMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50252000 (2-(3-hydroxy-2-(2-(methylsulfonyl)acetamido)-2,3-d...) Show SMILES CS(=O)(=O)CC(=O)N=c1scc(CC(O)=O)n1O |w:7.6| Show InChI InChI=1S/C8H10N2O6S2/c1-18(15,16)4-6(11)9-8-10(14)5(3-17-8)2-7(12)13/h3,14H,2,4H2,1H3,(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assay				Bioorg Med Chem Lett 18: 3925-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.031 BindingDB Entry DOI: 10.7270/Q2XW4JM5
					More data for this Ligand-Target Pair