BDBM50252021 4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benzamide::CHEMBL451165

SMILES: CNCc1cc(ccc1Cc1ccc(Cl)c(Cl)c1)C(N)=O

InChI Key: InChIKey=GYURBKTVOWBCTD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50252021 (4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benz...) Show SMILES CNCc1cc(ccc1Cc1ccc(Cl)c(Cl)c1)C(N)=O Show InChI InChI=1S/C16H16Cl2N2O/c1-20-9-13-8-12(16(19)21)4-3-11(13)6-10-2-5-14(17)15(18)7-10/h2-5,7-8,20H,6,9H2,1H3,(H2,19,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4018-21 (2008) Article DOI: 10.1016/j.bmcl.2008.06.001 BindingDB Entry DOI: 10.7270/Q2W37W4X
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50252021 (4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benz...) Show SMILES CNCc1cc(ccc1Cc1ccc(Cl)c(Cl)c1)C(N)=O Show InChI InChI=1S/C16H16Cl2N2O/c1-20-9-13-8-12(16(19)21)4-3-11(13)6-10-2-5-14(17)15(18)7-10/h2-5,7-8,20H,6,9H2,1H3,(H2,19,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4018-21 (2008) Article DOI: 10.1016/j.bmcl.2008.06.001 BindingDB Entry DOI: 10.7270/Q2W37W4X
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50252021 (4-(3,4-dichlorobenzyl)-3-((methylamino)methyl)benz...) Show SMILES CNCc1cc(ccc1Cc1ccc(Cl)c(Cl)c1)C(N)=O Show InChI InChI=1S/C16H16Cl2N2O/c1-20-9-13-8-12(16(19)21)4-3-11(13)6-10-2-5-14(17)15(18)7-10/h2-5,7-8,20H,6,9H2,1H3,(H2,19,21)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4018-21 (2008) Article DOI: 10.1016/j.bmcl.2008.06.001 BindingDB Entry DOI: 10.7270/Q2W37W4X
					More data for this Ligand-Target Pair