BDBM50252312 CHEMBL482302::N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfonyl)piperidin-4-yl)-3,4-dichlorobenzamide

SMILES: Clc1ccc(cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1

InChI Key: InChIKey=OZEUXSUCNVQZSI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50252312 (CHEMBL482302 | N-(1-(3-bromo-4-(piperidin-4-yloxy)...) Show SMILES Clc1ccc(cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 Show InChI InChI=1S/C23H26BrCl2N3O4S/c24-19-14-18(2-4-22(19)33-17-5-9-27-10-6-17)34(31,32)29-11-7-16(8-12-29)28-23(30)15-1-3-20(25)21(26)13-15/h1-4,13-14,16-17,27H,5-12H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
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