BDBM50252359 (R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic acid::CHEMBL504772

SMILES: NC(C(O)=O)c1ccnn1O

InChI Key: InChIKey=IICRPKTXGWIJCY-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2A receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair