BDBM50252427 (R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acetic acid::CHEMBL453769

SMILES: CCCc1cnn(O)c1C(N)C(O)=O

InChI Key: InChIKey=SSPXLOGHCJIQFQ-UHFFFAOYSA-N

Data: 3 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252427 ((R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acet...) Show SMILES CCCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C8H13N3O3/c1-2-3-5-4-10-11(14)7(5)6(9)8(12)13/h4,6,14H,2-3,9H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252427 ((R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acet...) Show SMILES CCCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C8H13N3O3/c1-2-3-5-4-10-11(14)7(5)6(9)8(12)13/h4,6,14H,2-3,9H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.53E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252427 ((R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acet...) Show SMILES CCCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C8H13N3O3/c1-2-3-5-4-10-11(14)7(5)6(9)8(12)13/h4,6,14H,2-3,9H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.29E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair