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SMILES: OC(=O)c1cn(-c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2c1=O

InChI Key: InChIKey=PPSCWVMHYJJOBZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252611   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))		BDBM50252611
PNG
(5,6,7,8-Tetrafluoro-4-oxo-1-(pentafluoro-phenyl)-1...)
Show SMILES OC(=O)c1cn(-c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2c1=O |(15.58,3.17,;14.25,3.94,;14.24,5.48,;12.92,3.17,;12.92,1.61,;11.58,.83,;11.59,-.7,;12.92,-1.46,;14.24,-.68,;12.93,-2.99,;14.26,-3.76,;11.59,-3.78,;11.6,-5.31,;10.26,-3.01,;8.92,-3.78,;10.25,-1.47,;8.91,-2.23,;10.24,1.6,;8.9,.83,;8.9,-.7,;7.57,1.6,;6.23,.84,;7.57,3.15,;6.23,3.92,;8.9,3.92,;8.89,5.46,;10.23,3.15,;11.57,3.94,;11.56,5.48,)|
Show InChI InChI=1S/C16H2F9NO3/c17-4-3-13(10(23)7(20)5(4)18)26(1-2(15(3)27)16(28)29)14-11(24)8(21)6(19)9(22)12(14)25/h1H,(H,28,29)
PDB

KEGG

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Similars
Article
PubMed
n/an/an/an/a 4.60E+4n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of STAT3 Y705 phosphorylation in human U266 cells by western blot analysis

J Med Chem 51: 4115-21 (2008)


Article DOI: 10.1021/jm701271y
BindingDB Entry DOI: 10.7270/Q2B27V3R
More data for this
Ligand-Target Pair